Oncogenic truncation of the first repeat of c-Myb decreases DNA binding in vitro and in vivo.
Oncogenic activation of c-Myb in both avian and murine systems often involves N-terminal truncation. In particular, the first of three DNA-binding repeats in c-Myb has been largely deleted during the genesis of the v-myb oncogenes of avian myeloblastosis virus and E26 avian leukemia virus. This find...
Spremljeno u:
| Izdano u: | Mol Cell Biol |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
1993
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364804/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8246954/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.12.7334-7348.1993 |
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