Quantitative Dissection and Stoichiometry Determination of the Human SET1/MLL Histone Methyltransferase Complexes

Methylation of lysine 4 on histone H3 (H3K4) at promoters is tightly linked to transcriptional regulation in human cells. At least six different COMPASS-like multisubunit (SET1/MLL) complexes that contain methyltransferase activity for H3K4 have been described, but a comprehensive and quantitative a...

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Main Authors: van Nuland, Rick, Smits, Arne H., Pallaki, Paschalina, Jansen, Pascal W. T. C., Vermeulen, Michiel, Timmers, H. T. Marc
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647974/
https://ncbi.nlm.nih.gov/pubmed/23508102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01742-12
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