Evaluation of Methods for Testing the Susceptibility of Clinical Mycobacterium tuberculosis Isolates to Pyrazinamide

Pyrazinamide (PZA) is a first-line antituberculosis (anti-TB) drug capable of killing nonreplicating, persistent Mycobacterium tuberculosis. However, reliable testing of the susceptibility of M. tuberculosis to PZA is challenging. Using 432 clinical M. tuberculosis isolates, we compared the performa...

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Bibliographic Details
Main Authors: Cui, Zhenling, Wang, Jie, Lu, Junmei, Huang, Xiaochen, Zheng, Ruijuan, Hu, Zhongyi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Mycobacteriology and Aerobic Actinomycetes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647927/
https://ncbi.nlm.nih.gov/pubmed/23390285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.03197-12
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