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Using Azido Analogue of S-Adenosyl-L-methionine for Bioorthogonal Profiling of Protein Methylation (BPPM)
Protein methyltransferases (PMTs) utilize S-adenosyl-L-methionine as a cofactor and deliver its sulfonium methyl moiety to diverse substrates. These methylation events can lead to meaningful biological outcomes from transcriptional activation/silencing to cell cycle regulation. With the long-term go...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3647616/ https://ncbi.nlm.nih.gov/pubmed/23667794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470559277.ch120240 |
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