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Using Azido Analogue of S-Adenosyl-L-methionine for Bioorthogonal Profiling of Protein Methylation (BPPM)

Protein methyltransferases (PMTs) utilize S-adenosyl-L-methionine as a cofactor and deliver its sulfonium methyl moiety to diverse substrates. These methylation events can lead to meaningful biological outcomes from transcriptional activation/silencing to cell cycle regulation. With the long-term go...

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Detalhes bibliográficos
Main Authors: Blum, Gil, Islam, Kabirul, Luo, Minkui
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647616/
https://ncbi.nlm.nih.gov/pubmed/23667794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470559277.ch120240
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