Novel ionically crosslinked casein nanoparticles for flutamide delivery: formulation, characterization, and in vivo pharmacokinetics

A novel particulate delivery matrix based on ionically crosslinked casein (CAS) nanoparticles was developed for controlled release of the poorly soluble anticancer drug flutamide (FLT). Nanoparticles were fabricated via oil-in-water emulsification then stabilized by ionic crosslinking of the positiv...

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Autors principals: Elzoghby, Ahmed O, Helmy, Maged W, Samy, Wael M, Elgindy, Nazik A
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2013
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647443/
https://ncbi.nlm.nih.gov/pubmed/23658490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S40674
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