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Pharmacokinetics of flutamide in patients with renal insufficiency

AIMS: The aim of this study was to determine the pharmacokinetic parameters of flutamide, a nonsteroidal antiandrogenic compound, and its pharmacologically active metabolite, hydroxyflutamide, in renal insufficiency. Haemodialysis (HD) clearance of flutamide and hydroxyflutamide was also determined....

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Détails bibliographiques
Auteurs principaux: Anjum, S, Swan, S K, Lambrecht, L J, Radwanski, E, Cutler, D L, Affrime, M B, Halstenson, C E
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014198/
https://ncbi.nlm.nih.gov/pubmed/10073738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00831.x
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