Functional role of GTPase-activating protein in cell transformation by pp60v-src.

Morphological transformation of NIH 3T3 cells was observed following coexpression of a portion of the ras GTPase-activating protein (GAP) comprising the amino terminus (GAP-N) and a mutant of v-src (MDSRC) lacking the membrane-localizing sequence. Cells expressing either of these genes alone remaine...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: DeClue, J E, Vass, W C, Johnson, M R, Stacey, D W, Lowy, D R
Format: Artigo
Langue:Inglês
Publié: 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC364742/
https://ncbi.nlm.nih.gov/pubmed/7692232
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