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Mapping Conformational Dynamics of Proteins Using Torsional Dynamics Simulations

All-atom molecular dynamics simulations are widely used to study the flexibility of protein conformations. However, enhanced sampling techniques are required for simulating protein dynamics that occur on the millisecond timescale. In this work, we show that torsional molecular dynamics simulations e...

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Detalhes bibliográficos
Main Authors: Gangupomu, Vamshi K., Wagner, Jeffrey R., Park, In-Hee, Jain, Abhinandan, Vaidehi, Nagarajan
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647154/
https://ncbi.nlm.nih.gov/pubmed/23663843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.01.050
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