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In and out of the bull’s eye: PKCs in the immunological synapse
The immunological synapse (IS) formed between immune cells and antigen-presenting cells (APCs) provides a platform for signaling. Protein kinase C-θ (PKC-θ) localizes in the T cell IS within the central supramolecular activation cluster (cSMAC), where it associates with CD28 and mediates TCR/CD28 si...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3647024/ https://ncbi.nlm.nih.gov/pubmed/23428395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2013.01.002 |
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