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IL-21 Is Required for Optimal Antibody Production and T Cell Responses during Chronic Toxoplasma gondii Infection

Previous studies have indicated that Il21r (−/−) mice chronically infected with Toxoplasma gondii display a defect in serum IgG; however, the basis for this antibody defect was not defined and questions remain about the role of IL-21 in promoting the production of IL-10, which is required to limit i...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Stumhofer, Jason S., Silver, Jonathan S., Hunter, Christopher A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647013/
https://ncbi.nlm.nih.gov/pubmed/23667536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062889
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