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Structure and dynamics of molecular networks: A novel paradigm of drug discovery: A comprehensive review

Despite considerable progress in genome- and proteome-based high-throughput screening methods and in rational drug design, the increase in approved drugs in the past decade did not match the increase of drug development costs. Network description and analysis not only gives a systems-level understan...

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Bibliografiske detaljer
Main Authors: Csermely, Peter, Korcsmáros, Tamás, Kiss, Huba J.M., London, Gábor, Nussinov, Ruth
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647006/
https://ncbi.nlm.nih.gov/pubmed/23384594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2013.01.016
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