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Structure and dynamics of molecular networks: A novel paradigm of drug discovery: A comprehensive review

Despite considerable progress in genome- and proteome-based high-throughput screening methods and in rational drug design, the increase in approved drugs in the past decade did not match the increase of drug development costs. Network description and analysis not only gives a systems-level understan...

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Autors principals: Csermely, Peter, Korcsmáros, Tamás, Kiss, Huba J.M., London, Gábor, Nussinov, Ruth
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647006/
https://ncbi.nlm.nih.gov/pubmed/23384594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2013.01.016
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