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Imine Reductases: A Comparison of Glutamate Dehydrogenase to Ketimine Reductases in the Brain

A key intermediate in the glutamate dehydrogenase (GDH)-catalyzed reaction is an imine. Mechanistically, therefore, GDH exhibits similarities to the ketimine reductases. In the current review, we briefly discuss (a) the metabolic importance of the GDH reaction in liver and brain, (b) the mechanistic...

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Detalhes bibliográficos
Main Authors: Hallen, André, Jamie, Joanne F., Cooper, Arthur J. L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646986/
https://ncbi.nlm.nih.gov/pubmed/23314864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-012-0964-1
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