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Engineering T Cell Function Using Chimeric Antigen Receptors Identified Using a DNA Library Approach

Genetic engineering of cellular function holds much promise for the treatment of a variety of diseases including gene deficiencies and cancer. However, engineering the full complement of cellular functions can be a daunting genetic exercise since many molecular triggers need to be activated to achie...

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Detalhes bibliográficos
Main Authors: Duong, Connie P. M., Westwood, Jennifer A., Yong, Carmen S. M., Murphy, Amanda, Devaud, Christel, John, Liza B., Darcy, Phillip K., Kershaw, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646939/
https://ncbi.nlm.nih.gov/pubmed/23667569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063037
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