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κ-Opioid Receptor Stimulation Improves Endothelial Function in Hypoxic Pulmonary Hypertension

The present study was designed to investigate the effect of κ-opioid receptor stimulation with U50,488H on endothelial function and underlying mechanism in rats with hypoxic pulmonary hypertension (HPH). Chronic hypoxia-induced HPH was simulated by exposing the rats to 10% oxygen for 2 wk. After hyp...

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Detalles Bibliográficos
Main Authors: Wu, Qi, Wang, Hai-Yan, Li, Juan, Zhou, Peng, Wang, Qiu-Lin, Zhao, Lei, Fan, Rong, Wang, Yue-Min, Xu, Xue-Zeng, Yi, Ding-Hua, Yu, Shi-Qiang, Pei, Jian-Ming
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646880/
https://ncbi.nlm.nih.gov/pubmed/23667430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060850
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