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Hypertensive state, independent of hypertrophy, exhibits an attenuated decrease in systolic function on cardiac κ-opioid receptor stimulation

Opioids/opiates are commonly administered to alleviate pain, unload the heart, or decrease breathlessness in patients with advanced heart failure. As such, it is important to evaluate whether the myocardial opioidergic system is altered in cardiac disease. A hamster model of spontaneous hypertension...

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Autores principales: Bolte, Craig, Newman, Gilbert, Schultz, Jo El J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670690/
https://ncbi.nlm.nih.gov/pubmed/19181965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00909.2008
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