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OVEREXPRESSION OF ORNITHINE DECARBOXYLASE DECREASES VENTRICULAR SYSTOLIC FUNCTION DURING INDUCTION OF CARDIAC HYPERTROPHY

Ornithine decarboxylase (ODC), the first enzyme of polyamine metabolism, is rapidly upregulated in response to agents that induce a pathological cardiac hypertrophy. Transgenic mice overexpressing ODC in the heart (MHC-ODC mice) experience a much more dramatic left ventricular hypertrophy in respons...

詳細記述

保存先:
書誌詳細
出版年:Amino Acids
主要な著者: Giordano, Emanuele, Hillary, Rebecca A., Vary, Thomas C., Pegg, Anthony E., Sumner, Andrew D., Caldarera, Claudio M., Zhang, Xue-Qian, Song, Jianliang, Wang, JuFang, Cheung, Joseph Y., Shantz, Lisa M.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416219/
https://ncbi.nlm.nih.gov/pubmed/21814794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-011-1023-y
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