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OVEREXPRESSION OF ORNITHINE DECARBOXYLASE DECREASES VENTRICULAR SYSTOLIC FUNCTION DURING INDUCTION OF CARDIAC HYPERTROPHY
Ornithine decarboxylase (ODC), the first enzyme of polyamine metabolism, is rapidly upregulated in response to agents that induce a pathological cardiac hypertrophy. Transgenic mice overexpressing ODC in the heart (MHC-ODC mice) experience a much more dramatic left ventricular hypertrophy in respons...
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| 出版年: | Amino Acids |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4416219/ https://ncbi.nlm.nih.gov/pubmed/21814794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00726-011-1023-y |
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