Transcriptional up-regulation of the mouse cytosolic glutathione peroxidase gene in erythroid cells is due to a tissue-specific 3' enhancer containing functionally important CACC/GT motifs and binding sites for GATA and Ets transcription factors.

Nuclear run-on experiments have shown that the high level of expression of the mouse cytosolic glutathione peroxidase mRNA in erythroid cells is due to up-regulation of the gene at the transcriptional level. Studies of the chromatin structure around the cytosolic glutathione peroxidase gene have rev...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	O'Prey, J, Ramsay, S, Chambers, I, Harrison, P R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364688/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8413228/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.10.6290-6303.1993
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