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Tissue-specific regulation of the rabbit 15-lipoxygenase gene in erythroid cells by a transcriptional silencer.

The 15-lipoxygenase (lox) gene is expressed in a tissue-specific manner, predominantly in erythroid cells but also in airway epithelial cells and eosinophils. We demonstrate in this report that the 5' flanking DNA of the 15-lox gene contains sequences which down-regulate its activity in a varie...

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Autori principali: O'Prey, J, Harrison, P R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC307263/
https://ncbi.nlm.nih.gov/pubmed/7478994
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