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Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation
Parkin, an E3 ubiquitin ligase well known for its role in the pathogenesis of juvenile Parkinson disease, has been considered as a candidate tumor suppressor in certain types of cancer. It remains unknown whether parkin is involved in the development of pancreatic cancer, the fourth leading cause of...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3646869/ https://ncbi.nlm.nih.gov/pubmed/23470638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24215 |
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