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Parkin deficiency contributes to pancreatic tumorigenesis by inducing spindle multipolarity and misorientation

Parkin, an E3 ubiquitin ligase well known for its role in the pathogenesis of juvenile Parkinson disease, has been considered as a candidate tumor suppressor in certain types of cancer. It remains unknown whether parkin is involved in the development of pancreatic cancer, the fourth leading cause of...

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Detalhes bibliográficos
Main Authors: Sun, Xiaodong, Liu, Min, Hao, Jihui, Li, Dengwen, Luo, Youguang, Wang, Xiuchao, Yang, Yunfan, Li, Fang, Shui, Wenqing, Chen, Quan, Zhou, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646869/
https://ncbi.nlm.nih.gov/pubmed/23470638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24215
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