Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma

Urothelial cell carcinoma (UCC) is the second most common genitourinary malignant disease in the USA, and tobacco smoking is the major known risk factor for UCC development. Exposure to carcinogens, such as those contained in tobacco smoke, is known to directly or indirectly damage DNA, causing muta...

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Main Authors: Brait, Mariana, Munari, Enrico, LeBron, Cynthia, Noordhuis, Maartje G., Begum, Shahnaz, Michailidi, Christina, Gonzalez-Roibon, Nilda, Maldonado, Leonel, Sen, Tanusree, Guerrero-Preston, Rafael, Cope, Leslie, Parrella, Paola, Fazio, Vito Michele, Ha, Patrick K., Netto, George J., Sidransky, David, Hoque, Mohammad O.
פורמט: Artigo
שפה:Inglês
יצא לאור: Landes Bioscience 2013
נושאים:
Report
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646862/
https://ncbi.nlm.nih.gov/pubmed/23435205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24050
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