Administration of Bleomycin via the Oropharyngeal Aspiration Route Leads to Sustained Lung Fibrosis in Mice and Rats as Quantified by UTE-MRI and Histology

Pulmonary fibrosis can be experimentally induced in small rodents by bleomycin. The antibiotic is usually administered via the intratracheal or intranasal routes. In the present study, we investigated the oropharyngeal aspiration of bleomycin as an alternative route for the induction of lung fibrosi...

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Główni autorzy: Egger, Christine, Cannet, Catherine, Gérard, Christelle, Jarman, Elizabeth, Jarai, Gabor, Feige, Agnès, Suply, Thomas, Micard, Arthur, Dunbar, Andrew, Tigani, Bruno, Beckmann, Nicolau
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2013
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646779/
https://ncbi.nlm.nih.gov/pubmed/23667616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063432
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