Administration of Bleomycin via the Oropharyngeal Aspiration Route Leads to Sustained Lung Fibrosis in Mice and Rats as Quantified by UTE-MRI and Histology

Pulmonary fibrosis can be experimentally induced in small rodents by bleomycin. The antibiotic is usually administered via the intratracheal or intranasal routes. In the present study, we investigated the oropharyngeal aspiration of bleomycin as an alternative route for the induction of lung fibrosi...

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Detalhes bibliográficos
Main Authors: Egger, Christine, Cannet, Catherine, Gérard, Christelle, Jarman, Elizabeth, Jarai, Gabor, Feige, Agnès, Suply, Thomas, Micard, Arthur, Dunbar, Andrew, Tigani, Bruno, Beckmann, Nicolau
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646779/
https://ncbi.nlm.nih.gov/pubmed/23667616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063432
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