Administration of Bleomycin via the Oropharyngeal Aspiration Route Leads to Sustained Lung Fibrosis in Mice and Rats as Quantified by UTE-MRI and Histology

Pulmonary fibrosis can be experimentally induced in small rodents by bleomycin. The antibiotic is usually administered via the intratracheal or intranasal routes. In the present study, we investigated the oropharyngeal aspiration of bleomycin as an alternative route for the induction of lung fibrosi...

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Autori principali: Egger, Christine, Cannet, Catherine, Gérard, Christelle, Jarman, Elizabeth, Jarai, Gabor, Feige, Agnès, Suply, Thomas, Micard, Arthur, Dunbar, Andrew, Tigani, Bruno, Beckmann, Nicolau
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646779/
https://ncbi.nlm.nih.gov/pubmed/23667616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063432
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