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Raised Intraocular Pressure as a Potential Risk Factor for Visual Loss in Leber Hereditary Optic Neuropathy

Leber Hereditary Optic Neuropathy (LHON) is an important cause of inherited mitochondrial blindness among young adults. The majority of patients carry one of three mitochondrial DNA (mtDNA) point mutations: m.3460G>A, m.11778G>A and m.14484T>C, all of which affect critical complex I subunit...

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Bibliografiske detaljer
Main Authors: Thouin, Anais, Griffiths, Philip G., Hudson, Gavin, Chinnery, Patrick F., Yu-Wai-Man, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646743/
https://ncbi.nlm.nih.gov/pubmed/23667621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063446
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