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Raised Intraocular Pressure as a Potential Risk Factor for Visual Loss in Leber Hereditary Optic Neuropathy

Leber Hereditary Optic Neuropathy (LHON) is an important cause of inherited mitochondrial blindness among young adults. The majority of patients carry one of three mitochondrial DNA (mtDNA) point mutations: m.3460G>A, m.11778G>A and m.14484T>C, all of which affect critical complex I subunit...

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Detalhes bibliográficos
Main Authors: Thouin, Anais, Griffiths, Philip G., Hudson, Gavin, Chinnery, Patrick F., Yu-Wai-Man, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646743/
https://ncbi.nlm.nih.gov/pubmed/23667621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063446
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