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Combined tissue factor pathway inhibitor and thrombomodulin deficiency produces an augmented hypercoagulable state with tissue-specific fibrin deposition

BACKGROUND AND OBJECTIVE: Tissue factor pathway inhibitor (TFPI) and thrombomodulin (TM) are endothelial-associated anticoagulant proteins thought to control hemostasis in specific vascular beds. Here, we have examined the consequences of TFPI deficiency in the presence of a compounding procoagulant...

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Autori principali: Maroney, S. A., Cooley, B. C., Sood, R., Weiler, H., Mast, A. E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646640/
https://ncbi.nlm.nih.gov/pubmed/17973652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2007.02817.x
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