p53 integrates host defense and cell fate during bacterial pneumonia

Cancer and infection are predominant causes of human mortality and derive, respectively, from inadequate genomic and host defenses against environmental agents. The transcription factor p53 plays a central role in human tumor suppression. Despite its expression in immune cells and broad responsivene...

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Main Authors: Madenspacher, Jennifer H., Azzam, Kathleen M., Gowdy, Kymberly M., Malcolm, Kenneth C., Nick, Jerry A., Dixon, Darlene, Aloor, Jim J., Draper, David W., Guardiola, John J., Shatz, Maria, Menendez, Daniel, Lowe, Julie, Lu, Jun, Bushel, Pierre, Li, Leping, Merrick, B. Alex, Resnick, Michael A., Fessler, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646498/
https://ncbi.nlm.nih.gov/pubmed/23630228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121674
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