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ATP-binding Cassette Transporter G1 Deficiency Dysregulates Host Defense in the Lung

Rationale: Mice with genetic deletion of the cholesterol efflux transporter, ATP-binding cassette (ABC) G1, have pulmonary lipidosis and chronic pulmonary inflammation. Whether ABCG1 regulates host defense is unknown. Objectives: To determine whether ABCG1 regulates pulmonary innate immunity and hos...

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Detalhes bibliográficos
Main Authors: Draper, David W., Madenspacher, Jennifer H., Dixon, Darlene, King, Debra H., Remaley, Alan T., Fessler, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921600/
https://ncbi.nlm.nih.gov/pubmed/20395559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200910-1580OC
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