Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3(+) dendritic cells at cross presentation

Human BDCA3(+) dendritic cells (DCs), the proposed equivalent to mouse CD8α(+) DCs, are widely thought to cross present antigens on MHC class I (MHCI) molecules more efficiently than other DC populations. If true, it is unclear whether this reflects specialization for cross presentation or a general...

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Main Authors: Cohn, Lillian, Chatterjee, Bithi, Esselborn, Filipp, Smed-Sörensen, Anna, Nakamura, Norihiro, Chalouni, Cécile, Lee, Byoung-Chul, Vandlen, Richard, Keler, Tibor, Lauer, Peter, Brockstedt, Dirk, Mellman, Ira, Delamarre, Lélia
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646496/
https://ncbi.nlm.nih.gov/pubmed/23569326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121251
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