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Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3(+) dendritic cells at cross presentation
Human BDCA3(+) dendritic cells (DCs), the proposed equivalent to mouse CD8α(+) DCs, are widely thought to cross present antigens on MHC class I (MHCI) molecules more efficiently than other DC populations. If true, it is unclear whether this reflects specialization for cross presentation or a general...
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| Главные авторы: | , , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3646496/ https://ncbi.nlm.nih.gov/pubmed/23569326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121251 |
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