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In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation

Numerous studies have described the altered expression and the causal role of microRNAs (miRNAs) in human cancer. However, to date, efforts to modulate miRNA levels for therapeutic purposes have been challenging to implement. Here we find that nucleolin (NCL), a major nucleolar protein, posttranscri...

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Bibliografische gegevens
Hoofdauteurs: Pichiorri, Flavia, Palmieri, Dario, De Luca, Luciana, Consiglio, Jessica, You, Jia, Rocci, Alberto, Talabere, Tiffany, Piovan, Claudia, Lagana, Alessandro, Cascione, Luciano, Guan, Jingwen, Gasparini, Pierluigi, Balatti, Veronica, Nuovo, Gerard, Coppola, Vincenzo, Hofmeister, Craig C., Marcucci, Guido, Byrd, John C., Volinia, Stefano, Shapiro, Charles L., Freitas, Michael A., Croce, Carlo M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646490/
https://ncbi.nlm.nih.gov/pubmed/23610125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120950
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