Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineages

Bone homeostasis is maintained by the coupled actions of hematopoietic bone-resorbing osteoclasts (OCs) and mesenchymal bone-forming osteoblasts (OBs). Here we identify early B cell factor 1 (Ebf1) and the transcriptional coregulator Zfp521 as components of the machinery that regulates bone homeosta...

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Auteurs principaux: Kiviranta, Riku, Yamana, Kei, Saito, Hiroaki, Ho, Daniel K., Laine, Julius, Tarkkonen, Kati, Nieminen-Pihala, Vappu, Hesse, Eric, Correa, Diego, Määttä, Jorma, Tessarollo, Lino, Rosen, Evan D., Horne, William C., Jenkins, Nancy A., Copeland, Neal G., Warming, Soren, Baron, Roland
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646489/
https://ncbi.nlm.nih.gov/pubmed/23569325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121187
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