The Antiviral Effector IFITM3 Disrupts Intracellular Cholesterol Homeostasis to Block Viral Entry

Vesicle-membrane-protein-associated protein A (VAPA) and oxysterol-binding protein (OSBP) regulate intracellular cholesterol homeostasis, which is required for many virus infections. During entry, viruses or virus-containing vesicles can fuse with endosomal membranes to mediate the cytosolic release...

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Autors principals: Amini-Bavil-Olyaee, Samad, Choi, Youn Jung, Lee, Jun Han, Shi, Mude, Huang, I-Chueh, Farzan, Michael, Jung, Jae U.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Inc. 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646482/
https://ncbi.nlm.nih.gov/pubmed/23601107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.03.006
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