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Bioorthogonal Labeling of 5-Hydroxymethylcytosine in Genomic DNA and Diazirine-Based DNA Photo-Cross-Linking Probes

DNA is not merely a combination of four genetic codes, namely A, T, C, and G. It also contains minor modifications that play crucial roles throughout biology. For example, the fifth DNA base, 5-methylcytosine (5-mC), which accounts for ~1% of all the nucleotides in mammalian genomic DNA, is a vital...

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Autori principali: SONG, CHUN-XIAO, HE, CHUAN
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646476/
https://ncbi.nlm.nih.gov/pubmed/21539303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar2000502
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