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Simultaneous blockade of programmed death 1 and vascular endothelial growth factor receptor 2 (VEGFR2) induces synergistic anti-tumour effect in vivo

Recent basic and clinical studies have shown that the programmed death ligand (PD-L)/PD-1 pathway has a significant role in tumour immunity, and its blockade has a therapeutic potential against several human cancers. We hypothesized that anti-angiogeneic treatment might augment the efficacy of PD-1...

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Bibliografske podrobnosti
Main Authors: Yasuda, S, Sho, M, Yamato, I, Yoshiji, H, Wakatsuki, K, Nishiwada, S, Yagita, H, Nakajima, Y
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646450/
https://ncbi.nlm.nih.gov/pubmed/23600839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12069
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