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Blockade of VEGFR1 and 2 Suppresses Pathological Angiogenesis and Vascular Leakage in the Eye

OBJECTIVE: VEGFR1 and 2 signaling have both been increasingly shown to mediate complications of ischemic retinopathies, including retinopathy of prematurity (ROP), age-related macular degeneration (AMD), and diabetic retinopathy (DR). This study evaluates the effects of blocking VEGFR1 and 2 on path...

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Bibliographic Details
Main Authors: Huang, Hu, Shen, Jikui, Vinores, Stanley A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3120882/
https://ncbi.nlm.nih.gov/pubmed/21731737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021411
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