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Effects of combination therapy with dipeptidyl peptidase-IV and histone deacetylase inhibitors in the non-obese diabetic mouse model of type 1 diabetes

Type 1 diabetes (T1D) results from T helper type 1 (Th1)-mediated autoimmune destruction of insulin-producing β cells. Novel experimental therapies for T1D target immunomodulation, β cell survival and inflammation. We examined combination therapy with the dipeptidyl peptidase-IV inhibitor MK-626 and...

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Detalhes bibliográficos
Main Authors: Cabrera, S M, Colvin, S C, Tersey, S A, Maier, B, Nadler, J L, Mirmira, R G
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646436/
https://ncbi.nlm.nih.gov/pubmed/23600825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12068
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