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Top-Down Network Analysis to Drive Bottom-Up Modeling of Physiological Processes

Top-down analyses in systems biology can automatically find correlations among genes and proteins in large-scale datasets. However, it is often difficult to design experiments from these results. In contrast, bottom-up approaches painstakingly craft detailed models that can be simulated computationa...

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Detalhes bibliográficos
Main Authors: Poirel, Christopher L., Rodrigues, Richard R., Chen, Katherine C., Tyson, John J., Murali, T.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646337/
https://ncbi.nlm.nih.gov/pubmed/23641868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2012.0274
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