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Top-Down Network Analysis to Drive Bottom-Up Modeling of Physiological Processes
Top-down analyses in systems biology can automatically find correlations among genes and proteins in large-scale datasets. However, it is often difficult to design experiments from these results. In contrast, bottom-up approaches painstakingly craft detailed models that can be simulated computationa...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Mary Ann Liebert, Inc.
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3646337/ https://ncbi.nlm.nih.gov/pubmed/23641868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2012.0274 |
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