A viral long terminal repeat expressed in CD4+CD8+ precursors is downregulated in mature peripheral CD4-CD8+ or CD4+CD8- T cells.

The long terminal repeat from a thymotropic mouse mammary tumor virus variant, DMBA-LV, was used to drive the expression of two reporter genes, murine c-myc and human CD4, in transgenic mice. Expression was observed specifically in thymic immature cells. Expression of c-myc in these cells induced ol...

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Bibliographic Details
Main Authors: Paquette, Y, Doyon, L, Laperrière, A, Hanna, Z, Ball, J, Sekaly, R P, Jolicoeur, P
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC364609/
https://ncbi.nlm.nih.gov/pubmed/1321339
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