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C5a is not involved in experimental autoimmune myasthenia gravis pathogenesis

C5 deficient mice are highly resistant to experimental autoimmune myasthenia gravis (EAMG) despite intact immune response to acethylcholine receptor (AChR), validating the pivotal role played by membrane attack complex (MAC, C5b-9) in neuromuscular junction destruction. To distinguish the significan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qi, Huibin, Tüzün, Erdem, Allman, Windy, Saini, Shamsher S., Penabad, Zurina R., Pierangeli, Silvia, Christadoss, Premkumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645869/
https://ncbi.nlm.nih.gov/pubmed/18455242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2008.03.007
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