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Aptamers and Their Potential to Selectively Target Aspects of EGF, Wnt/β-Catenin and TGFβ–Smad Family Signaling

The smooth identification and low-cost production of highly specific agents that interfere with signaling cascades by targeting an active domain in surface receptors, cytoplasmic and nuclear effector proteins, remain important challenges in biomedical research. We propose that peptide aptamers can p...

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Detalles Bibliográficos
Main Authors: Conidi, Andrea, van den Berghe, Veronique, Huylebroeck, Danny
Formato: Artigo
Idioma:Inglês
Publicado: Molecular Diversity Preservation International (MDPI) 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645661/
https://ncbi.nlm.nih.gov/pubmed/23531534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14046690
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