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Aptamers and Their Potential to Selectively Target Aspects of EGF, Wnt/β-Catenin and TGFβ–Smad Family Signaling

The smooth identification and low-cost production of highly specific agents that interfere with signaling cascades by targeting an active domain in surface receptors, cytoplasmic and nuclear effector proteins, remain important challenges in biomedical research. We propose that peptide aptamers can p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Conidi, Andrea, van den Berghe, Veronique, Huylebroeck, Danny
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Diversity Preservation International (MDPI) 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645661/
https://ncbi.nlm.nih.gov/pubmed/23531534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms14046690
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