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The cardiac Na(+)-Ca(2+) exchanger has two cytoplasmic ion permeation pathways

The Na(+)-Ca(2+) exchanger (NCX) is a ubiquitously expressed plasma membrane protein. It plays a fundamental role in Ca(2+) homeostasis by moving Ca(2+) out of the cell using the electrochemical gradient of Na(+) as the driving force. Recent structural studies of a homologous archaebacterial exchang...

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Hlavní autoři: John, Scott A., Liao, Jun, Jiang, Youxing, Ottolia, Michela
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645563/
https://ncbi.nlm.nih.gov/pubmed/23589872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218751110
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