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Roles of Two Ca(2+)-binding Domains in Regulation of the Cardiac Na(+)-Ca(2+) Exchanger
We expressed full-length Na(+)-Ca(2+) exchangers (NCXs) with mutations in two Ca(2+)-binding domains (CBD1 and CBD2) to determine the roles of the CBDs in Ca(2+)-dependent regulation of NCX. CBD1 has four Ca(2+)-binding sites, and mutation of residues Asp(421) and Glu(451), which primarily coordinat...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Biochemistry and Molecular Biology
2009
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2781690/ https://ncbi.nlm.nih.gov/pubmed/19801651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.055434 |
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