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GroEL and CCT are catalytic unfoldases mediating out-of-cage polypeptide refolding without ATP
Chaperonins are cage-like complexes in which nonnative polypeptides prone to aggregation are thought to reach their native state optimally. However, they also may use ATP to unfold stably bound misfolded polypeptides and mediate the out-of-cage native refolding of large proteins. Here, we show that...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3645539/ https://ncbi.nlm.nih.gov/pubmed/23584019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219867110 |
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