Critical role for miR-181a/b-1 in agonist selection of invariant natural killer T cells

T-cell receptor (TCR) signal strength determines selection and lineage fate at the CD4(+)CD8(+) double-positive stage of intrathymic T-cell development. Members of the miR-181 family constitute the most abundantly expressed microRNA at this stage of T-cell development. Here we show that deletion of...

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Detalhes bibliográficos
Main Authors: Ziętara, Natalia, Łyszkiewicz, Marcin, Witzlau, Katrin, Naumann, Ronald, Hurwitz, Robert, Langemeier, Jörg, Bohne, Jens, Sandrock, Inga, Ballmaier, Matthias, Weiss, Siegfried, Prinz, Immo, Krueger, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645533/
https://ncbi.nlm.nih.gov/pubmed/23589855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221984110
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