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In vitro dissolution study of atorvastatin binary solid dispersion

The aim of the present study was to improve the solubility and dissolution rate of atorvastatin (ATV), a slight water-soluble drug, by solid dispersion (SD) technique using a hydrophilic carrier Poloxamer 188 (POL188). Physical mixing (PM) and solvent evaporation (SE) method were used to prepare ATV...

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Autori principali: Jahan, Rahat, Islam, Md. Saiful, Tanwir, Ahmad, Chowdhury, Jakir Ahmed
Natura: Artigo
Lingua:Inglês
Pubblicazione: Medknow Publications & Media Pvt Ltd 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645364/
https://ncbi.nlm.nih.gov/pubmed/23662278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2231-4040.107496
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