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In vitro dissolution study of atorvastatin binary solid dispersion
The aim of the present study was to improve the solubility and dissolution rate of atorvastatin (ATV), a slight water-soluble drug, by solid dispersion (SD) technique using a hydrophilic carrier Poloxamer 188 (POL188). Physical mixing (PM) and solvent evaporation (SE) method were used to prepare ATV...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Medknow Publications & Media Pvt Ltd
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3645364/ https://ncbi.nlm.nih.gov/pubmed/23662278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2231-4040.107496 |
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