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Loss of Epithelial Estrogen Receptor α Inhibits Estrogen Stimulated Prostate Proliferation and Squamous Metaplasia via In Vivo Tissue Selective Knockout Models

Squamous metaplasia (SQM) is a specific phenotype in response to estrogen in the prostate and estrogen receptor (ER) α is required to mediate this response. Previous studies utilizing tissue recombination with seminal vesicle (SV) mesenchyme and prostatic ductal tips from Wt and ERαKO mice suggested...

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Detalhes bibliográficos
Main Authors: Chen, Ming, Yeh, Chiuan-Ren, Chang, Hong-Chiang, Vitkus, Spencer, Wen, Xing-Qiao, Bhowmick, Neil A., Wolfe, Andrew, Yeh, Shuyuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3645347/
https://ncbi.nlm.nih.gov/pubmed/22069040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.2949
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